1.Ibogaine and Psychedelic Research:
  KRFI conducts clinical trial to investigate the effectiveness of ibogaine (a naturally occurring compound from the African iboga plant) and psychedelic entheogenic medicines ranging from psilocybin (the active compound in psychedelic mushrooms) in treating opioid use disorder (OUD), substance use disorders (SUD), TBI, PTSD, and Parkinson's disease, and other mental health conditions. The institute aims to provide scientific evidence for these substances' therapeutic potential through comprehensive mechanisms of action and biomarker research.

2. Private Public Sector Partnership for Opioid Abatement Matching Fund (OAMF):
  KRFI is actively engaged in a strategic effort to secure funding for opioid abatement** programs through PPP models for sustainable access to psychedelic therapies. This includes leveraging state-level funding to develop and implement evidence-based solutions for addiction treatment.

3. Global Collaboration for Health Equity:
  By advocating for Access for Benefit Sharing (ABS), KRFI works with indigenous communities, governments, and private sectors to ensure ethical practices in the development of plant-based drugs. This includes protecting the intellectual property (IP) and traditional knowledge of indigenous communities, while ensuring that they benefit from the commercialization of these natural medicines.

4. Policy Advocacy and Education:
  The institute focuses on policy reform and diplomatic PPP dialogue to create sustainable, globally-inclusive health frameworks. Through public educational programs and sustainable natural products resource management and building initiatives, KRFI prepares future leaders to advocate for PPP for ABS for good governance, health equity, and social justice in drug policy, with a specific emphasis on psychedelic therapeutics.

5. Clinical Trial Innovations:
  KRFI is engaged in clinical trials for its flagship products, Endabuse® and Remogen®, aimed at addressing addiction and neurological conditions. These trials will provide medical evidence for ibogaine and psilocybin treatments, paving the way for new, non-addictive therapies.

6. Sustainable Development through PPP for ibogaine and psychedelics:
  KRFI advocates for the sustainable development of natural products by working with indigenous communities in a transparent and fair sustainable partnership. The institute supports the development of supply chains for plant-based medicines, ensuring that the local communities have a direct stake in the economic benefits derived from the global demand for these therapeutics.

Key Programs

1. Private Sector Leadership in Access for Benefit Sharing:
This program focuses on sustainable agricultural practices and partnerships between private sectors, indigenous communities, and public entities. Participants gain a deep understanding of how conservation and ethical drug development can coexist.

2. Opioid Abatement Matching Fund PPP Global Partnership for ABS:
A specialized program aimed at fostering natural resources conflict resolution and creating sustainable economic systems in partnership with indigenous groups and their resources.

3. Public Policy for Health Equity and Good Governance:
This program helps policymakers and civil servants develop frameworks to ensure health equity, promote human rights, and enhance public participation in decision-making, especially in drug policy.

4. Private Sector Partnership Programs:
KRFI's Blockchain Supply Chain Security Blockchain initiatives is a programs to ensure transparency and sustainability in the supply of psychedelic medicines, creating traceable systems from plant to patient.

Global Partnerships

KRFI collaborates with a wide range of international civil societies, NGOs, academic institutions, and governments to ensure the development of sustainable and ethical drug policies. The institute’s Roundtable for PPP initiative brings together diverse stakeholders to foster collaboration and drive policy reform on a global scale, particularly around psychedelic therapeutics and mental health treatments.

Knowledge Recovery Institute private public sector partnership for opioid abatement matching fund global movement for mental health security and Opioid and substance abuse recovery, working through the innovative use of natural products like ibogaine and psilocybin. Through cross-sector partnerships, policy reform, and global education, KRFI seeks to revolutionize how society approaches mental health treatment and addiction recovery, while also ensuring that indigenous knowledge and cultures benefit from the recognition and protection of their contributions to modern medicine.